Immunglobuline A (IgA)

Synonyms: antibody, antigen-binding protein, immunoglobulin molecule, immunoprotein, serum protein

Julen Lux Baranano

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Julen Lux Baranano

1. Definition:

IgA is found primarily in mucosal areas and secretions and serves as the first line of defense against pathogens.

2. Characteristics and Function:

Appearance: IgA can exist as a monomer in serum, but is typically found as a dimer in secretions, linked by a J chain.
Function: Protects mucosal surfaces (e.g., respiratory and gastrointestinal tracts) by preventing adherence and invasion of pathogens.
Secretory form: In secretions such as saliva, tears, and breast milk, it is known as secretory IgA (sIgA) and plays a critical role in immune defense.
Immune barrier: IgA acts as a critical barrier to infection on mucosal surfaces, where it neutralizes viruses and bacteria before they enter the body.
Passive Immunity: IgA in breast milk provides passive immunity to infants during breast-feeding.

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Specialty

biology, immunology

Keywords

Last edit:

2024-12-26 19:22:21

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Immunglobuline A (IgA)

Julen Lux Baranano

Table of Contents

1. Definition:

2. Characteristics and Function:

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