Immunglobuline M (IgM)

Synonyms: antibody, immunoglobin, immunoglobulin molecule, immunprotein, serum globulin, serum protein

Julen Lux Baranano

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Julen Lux Baranano

1. Definition:

IgM is the first antibody produced in response to infection and is essential for the initial immune response.

2. Characteristics and Function:

Appearance: IgM typically exists as a pentamer consisting of five Y-shaped units linked by a J-chain, giving it a large size.
Function: It is highly effective at binding to pathogens and activating the complement system, leading to their destruction.
Early response: IgM is the first antibody produced by B cells upon encountering an antigen, making it critical for early defense against infection.
B cell receptor: In addition to its role in serum, IgM functions as a B cell receptor (BCR) on the surface of naive B cells and plays a role in their activation.
Agglutination: Its pentameric structure allows IgM to agglutinate (clump together) pathogens, facilitating their removal from the body.

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Specialty

biology, immunology

Keywords

Last edit:

2024-12-26 19:22:18

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Immunglobuline M (IgM)

Julen Lux Baranano

Table of Contents

1. Definition:

2. Characteristics and Function:

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