Dromotropic

edited by
Julius Loges

Table of Contents

1. Definition

Dromotropic refers to the influence on the conduction velocity of electrical impulses through the heart’s conduction system, particularly the atrioventricular (AV) node. A positive dromotropic effect increases conduction speed, while a negative dromotropic effect slows down the conduction of impulses, affecting the heart’s rhythm and coordination.

2. Influencing factors

2.1. Substances with postive dromotropic effects

  • Epinephrine (adrenaline)
  • Norepinephrine (noradrenaline)
  • Dopamine (at higher doses)
  • Isoproterenol
  • Dobutamine
  • Atropine

2.2.Substances with negative dromotropic effects

  • Beta-blockers (e.g., metoprolol, propranolol)
  • Calcium channel blockers (e.g., verapamil, diltiazem)
  • Digoxin
  • Adenosine
  • Amiodarone
  • Ivabradine

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Last edit:
2024-12-26 19:15:16
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