Eosinophils

edited by
Joshua Klemt,

Table of Contents

1. Definition

Eosinophils are a type of white blood cell that play a crucial role in the immune response by combating parasitic infections, mediating allergic reactions, and regulating inflammation.

3. Physiology

  • Absolute Count: This percentage corresponds to approximately 100 to 400 eosinophils per microliter (µL) of blood in a healthy individual
  • Percentage in Blood: Eosinophils typically account for 1-4% of total white blood cells
  • Eosinophilia: An increase in eosinophil count above the normal range
  • Eosinopenia: A decrease in eosinophil count below the normal range

2. Function

Defense Against Parasites:

  • larger parasites: helminths (worms)
  • release toxic granules that damage or kill these invaders

Mediation of Allergic Reactions:

  • allergic conditions like asthma and hay fever
  • releasing inflammatory mediators such as histamines
  • leukotrienes that contribute to tissue inflammation and hypersensitivity

Regulation of Immune Responses:

  • help modulate the activity of other immune cells, maintaining a balanced immune response

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Last edit:
2024-12-26 19:21:41
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