Feedback refers to a system whose output variable has a modulating effect on the input variable.
There are two different types of feedback:
Negative feedback (more frequent): For example, an enzyme at the start of a metabolic pathway is inhibited by high concentrations of the end product.
Positive feedback: enhances the regulatory effect (e.g. effect of estradiol on GnRH and LH secretion in the middle of the cycle)
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