Immunglobuline E (IgE)

edited by
Joshua Klemt,

Table of Contents

1. Definition:

IgE is primarily involved in allergic reactions and responses to parasitic infections.

2. Characteristics and function:

  • Appearance: IgE is a monomeric antibody similar in structure to IgG but with a different constant region.
  • Function: It binds to allergens and triggers the release of histamine and other inflammatory mediators from mast cells and basophils, resulting in allergic symptoms.
  • Role in allergy: Elevated levels of IgE are associated with allergic diseases such as asthma, hay fever, and anaphylaxis.
  • Parasitic Defense: IgE also plays a role in protecting the body from parasitic infections, particularly helminths (worms).
  • Minimal serum levels: IgE is present in very low concentrations in serum compared to other antibody classes, reflecting its specialized role.

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Last edit:
2024-12-26 19:22:16
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