Immunglobuline G (IgG)

Synonyms: antibody, immunoglobulin molecule, immunoprotein

Julen Lux Baranano

edited by

Julen Lux Baranano

1. Definition:

IgG is the most abundant antibody in the bloodstream, accounting for approximately 75-80% of serum antibodies.

2. Characteristics and Function:

Appearance: IgG is a monomeric antibody, consisting of a single Y-shaped unit.
Function: It provides long-term protection against pathogens by neutralizing toxins and viruses and is essential for opsonization, which enhances phagocytosis.
Placental transfer: IgG can cross the placenta and provide passive immunity to the fetus during pregnancy.
Subclasses: IgG has four subclasses (IgG1, IgG2, IgG3, and IgG4), each with slightly different roles and affinities for antigens.
Complement activation: IgG can activate the complement system, resulting in the destruction of pathogens.

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Specialty

biology, immunology

Keywords

Last edit:

2024-12-26 19:22:19

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Immunglobuline G (IgG)

Julen Lux Baranano

Table of Contents

1. Definition:

2. Characteristics and Function:

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