1. Definition
Pattern Recognition Receptors (PRRs) are proteins found on the surface or inside immune cells that detect and bind to conserved molecular patterns found on pathogens, known as PAMPs (pathogen-associated molecular patterns), initiating an immune response.
2. Types
- Toll-like Receptors (TLRs)
- Nod-like Receptors (NLRs)
- RIG-I-like Receptors (RLRs)
- C-type Lectin Receptors (CLRs)
- AIM2-like Receptors (ALRs)
- Scavenger Receptors
3. Cells with Pattern Recognition Receptors
- Macrophages
- Dendritic cells
- Neutrophils
- Monocytes
- Mast cells
- Eosinophils
- Basophils
- Natural killer (NK) cells
- B cells
- Epithelial cells
- Endothelial cells