1. Definition
Stroke volume (SV) refers to the amount of blood pumped out of the left ventricle during the heart’s contraction phase, known as systole.
2. Calculation
Stroke volume (SV) is calculated using the formula:
SV = End-Diastolic Volume (EDV) − End-Systolic Volume (ESV)
The typical stroke volume is approximately 70 to 100 milliliters and can readily increase to approximately 100 to 140 milliliters and even higher during periods of physical exertion.
3. Influencing Factors
The stroke volume (SV) is influenced by several factors:
Preload: increasing preload can increase SV because the myocardium expands more at a higher end-diastolic volume with proper ventricular compliance.
Contractility: Higher contractility increases SV by increasing myocardial contractions.
Afterload: Higher total peripheral resistance (TPR) and aortic pressure can decrease SV by increasing the force required to eject blood.
Heart rate: Although a very high heart rate does not directly affect SV, it can shorten the diastolic filling time and worsen coronary perfusion.
Together, these factors determine the volume of blood that the heart pumps with each beat. An augmentation in stroke volume affects cardiac output.